Alumni And Collaborators:
Muhammad Nabeel Ghayur (MPhil, 2002; PhD 2005),
Post-Doctoral Fellow, Department of Medicine, McMaster University ,
Hamilton L8N 4A6 , Ontario , Canada Ms Qaiser Jabeen (MPhil, 2001, PhD 2005), Assistant Professor, Department of Pharmacy, Islamia University, Bahawalpur Dr Sheikh Yaeesh (MPhil, 2005), Assistant Professor, Department of Pharmacology, Ziauddin Medical University , Clifton , Karachi Dr SIH Taqvi (PhD 2003) Assistant Professor, Federal Urdu University of Arts, Science and Technology, Karachi Dr Zahid A Butt (MSc 2002), Epidemiologist, WHO Office, National Institute of Health, Islamabad Dr Khalid Aftab, (PhD 1996) Associate Professor, Department of Pharmacology and Therapeutics, Foundation University Medical College , Rawalpindi
Collaborators Within The Aga Khan University:
Dr Sohail Qureshi |
Department of Biological and Biomedical Sciences |
Dr Kashif Majid |
Department of Biological and Biomedical Sciences |
Dr Dileep Rohra |
Department of Biological and Biomedical Sciences |
Dr Abdul Saeed |
Department of Biological and Biomedical Sciences |
Dr Arif Siddiqui |
Department of Biological and Biomedical Sciences |
Dr John Connor |
Department of Biological and Biomedical Sciences |
Dr Viqar Zaman |
Department of Microbiology and Pathology |
Dr Waris Qidwai |
Department of Family Medicine |
Dr Hasnain A Shah |
Department of Medicine |
Dr Tazeen Jafar |
Department of Medicine and Community Health Sciences |
Dr Shahla Siddiqui |
Department of Anaesthesia |
Collaborators within Pakistan
Dr M. Shoaib Akhtar, Meritorious Professor of
Pharmacology and Dean, Faculty of Veterinary Sciences, University of
Agriculture , Faisalabad Dr Zafar Iqbal, Associate Professor and Chairman, Department of Parasitology, University of Agriculture , Faisalabad Dr Zafar Iqbal, Professor, Department of Pharmacy, University of Peshawar , Peshawar Prof Ghulam Ali Qureshi, Director Research, Liaquat University of Health Sciences, Jamshoro Dr Fazal-e-Subhan, Associate Professor, Department of Pharmacy, University of Peshawar , Peshawar . Dr Shahida Perveen, Professor of Pharmacology, Faculty of Pharmacy, University of Karachi Dr Rafiq Alam Khan, Associate Professor and Head of Pharmacology Department, Faculty of Pharmacy, University of Karachi Prof
Sheikh Arshad Saeed, Dr Punjwani Center for Molecular Medicine and Drug
Research, International Center for Chemical Sciences, University of
Karachi, Karachi
Prof Mudassir Israr Zaidi, Department of Botany, University of Balochistan , Quetta
HEJ Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi
Dr Farzana Shaheen
Overseas Collaborators
Dr Peter J. Houghton, Editor, Journal of
Ethnopharmacology and Professor of Pharmacognosy, Department of
Pharmacy, King's College London , UK Dr M. Rais Mustafa,
Associate Professor and Acting Head, Department of Pharmacology, Faculty
of Medicine, University of Malaya, Kuala Lumpur, Malaysia Dr Evangeline C. Amor, Assistant Professor, Institute of Chemistry , University of the Philippines , Quezon City , Philippines Dr
Mustafa Ali Mohammad, Associate Professor, Department of Pharmacology,
Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia Prof Bilge Sener, Director, Institute of Pharmacy , Gazi University , Ankara , Turkey Prof Dr Joachim W. Herzig, President, University of Applied Sciences, Germany
Dr Shabbir Ahmed Tariq, Associate Professor, University Sabah , Malaysia
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Recent Publications
Gilani AH, Atta-ur-Rahman. Trends in
Ethnopharmacology. J Ethnopharmacol 2005; 100: 43-49 (perspective
article for a special issue of the journal on completion of its 100
volumes) Ghayur MN, Gilani AH. Ginger lowers blood
pressure through blockade of voltage-dependent calcium channels. J
Cardiovas Pharmacol 2005; 45, 74-80. Gilani AH, Shah AJ,
Ghayur MN, Majeed K. Pharmacological basis of for the use of turmeric in
gastrointestinal and respiratory disorders. Life Sci 2005; 76/26:
3089-3105. Malik F, Hussain S, Dil AS, Hannan A, Gilani
AH. Islamic Republic of Pakistan., Chapter 22, In: WHO Global Atlas of
Traditional, Complementary and Alternative Medicine 2005; (Map volume),
Editors: C.K. Ong, G. Bodeker, C. Grundy, G. Burford, K. Shein, World
Health Organization, Geneva, pp. 165-169 (book chapter) Gilani AH,
Ghayur MN, Khalid A, Zaheer-ul-Haq, Choudhary MI, Atta-ur-Rahman.
Presence of antispasmodic, antidiarrhoeal, antisecretory, calcium
antagonist and acetylcholinesterase inhibitory steroidal alkaloids
inSarcococca saligna. Planta Medica 2005; 71: 120-125.
Ghayur
MN, Gilani AH, Houghton P. Species differences in the gut stimulatory
effects of radish seeds. J Pharmac and Pharmacol 2005; 79: 1493-1501. Choudhary
MI, Nawaz SA, Zaheer-ul-Haq, Azim MK, Ghayur MN, Lodhi MA, Jalil S,
Khalid A, Ahmed A, Rode BM, Atta-ur-Rahman, Gilani AH, Ahmad VU.
Juliflorine: a potent natural#BM peripheral anionic-site- binding
inhibitor of acetylcholinesterase with calcium-channel blocking
potential, a leading candidate for Alzheimer's disease therapy. Biochem
Biophys Res Commun 2005; 332: 1171-1179. Rohra DK, Sharif
H, Zuberi H, Ghayur MN, Gilani AH. Acidosis-induced relaxation of
human mammary artery is due to activation of ATP-sensitive potassium
channels. Eur J Pharmacol 2005; 514: 175-181. Ghayur MN,
Gilani AH. Pharmacological basis for the use of Ginger in
gastrointestinal disorders. Diges Dis Sci 2005; 50: 1889-1897.
Choudhary
MI, Nawaz SA, Zaheer-ul-Haq, Lodhi MA, Ghayur MN, Jalil S, Riaz N,
Yousuf S, Malik A, Rode BM, Gilani AH, Atta-ur-Rahman. Withanolides, a
new class of natural cholinesterase inhibitors with calcium antagonistic
properties. Biochem Biophys Res Commun 2005; 334: 276-287 Gilani AH. Role of medicinal plants in modern medicine. Malay J Sci 2005; 24: 1-5 (review article). Amor
EC, Villaseñora IM, Ghayur MN, Gilani AH, Choudhary MI. Spasmolytic
flavonoids from Syzygium samarangense (Blume) Merr. & L.M. Perry.
Zeit Natur c 2005; 60: 67-71.
Gilani
AH, Jabeen Q, Ghayur MN, Janbaz KH, Akhtar MS. Studies on the
antihypertensive, antispasmodic, bronchodilator and hepatoprotective
activities of the Carum copticum seed extract. J Ethnopharmacol 2005;
98:127-135. Gilani AH, Yaeesh S, Jamal Q, Ghayur MN.
Hepatoprotective activity of aqueous-methanol extract of Artemisia
vulgaris. Phytother Res 2005; 19: 170-172. Butt ZA,
Gilani AH, Nanan D, Sheikh AL, White F. Quality of Pharmacies in
Pakistan: A Cross-sectional Survey. Int J Quality Health Care 2005; 17:
307-313. Gilani AH, Bashir S, Janbaz KH, Khan A.
Pharmacological basis for the use of Fumaria indica in constipation and
diarrhea. J Ethnopharmacol 2005; 96: 585-589.
Gilani
AH, Khan A, Shah AJ, Jabeen Q, Subhan F, Ghafar R. Antispasmodic and
blood pressure lowering effects of Valeriana wallichii are mediated
through K+ channel activation J Ethnopharmacol 2005; 100: 347-352. Gilani
AH, Ghayur MN. Ginger: from myths to reality. In:
Gottschalk-Batsschkus, C.E., Green, J.C. (Eds.), Ethnotherapies in the
cycle of life - Books on Demand/Ethnomed Institut für Ethnomedizin e.V.,
Munich, 2005 pp. 307-315 (book chapter). Gilani AH,
Ghayur MN. The betel nut chewing culture. In: Gottschalk-Batsschkus CE,
Green JC (Eds.), Ethnotherapies in the cycle of life - Books on
Demand/Ethnomed Institut für Ethnomedizin e.V., Munich, 2005 pp. 287-294
(book chapter). Gilani AH. Role of ethnopharmacology in
the development of modern medicine. In: Shinwar ZK, Watanabe T, Ali M,
Anwar R (Eds.) Proceedings of the International Symposium on Medicinal
Plants: Linkages beyond national boundaries, Al-Aziz Communications,
Peshawar 2005; pp. 192-197.
Ghayur
MN, Gilani AH, Afridi MB, Houghton PJ. Cardiovascular effects of ginger
aqueous extract and its phenolic constituents are mediated through
multiple pathways. Vascular Pharmacol 2005; 43(4): 234-241. Gilani
AH, Ghayur MN, Houghton PJ, Jabeen Q, Kazim SF, Jumani MI, Saeed SA.
Studies on the hypotensive, cardio-suppressant, vasodilator and
antiplatelet activities of betel nut crude extract and its constituents.
Int J Pharmacol 2006; 2 (1): 33-41 Gilani AH, Bukhari I,
Khan RA, Farman-ullah, Ahmad VU. Cholinomimetic and calcium channel
blocking activities of Carthamus oxycanth. Phytother Res 2005; 19:
679-683
Gilani AH, Bashir S,
Janbaz KH, Shah AJ. Presence of cholinergic and calcium channel blocking
activities explains the traditional use of Hibiscus rosasinensis in
constipation and diarrhea. J Ethnopharmacol 2005; 102: 289-294. Saeed
SA, Urfi MZS, Ali TM, Khimani FW, Gilani AH. Antioxidants: their role
in health and disease. Int J Pharmacol 2005; 1: 210-217 (review
article). Iqbal Z, Lateef M, Jabbar A, Ghayur, MN,
Gilani AH. In vitro and in vivo anthelmintic activity of Nicotiana
tabacum L. leaves against gastrointestinal nematodes of sheep. Phytother
Res 2005; 19: (in press).
Gilani
AH, Khan A, Subhan F, Khan M. Antispasmodic and bronchodilator
activities of St. John's Wort are putatively mediated through dual
inhibition of calcium influx and phosphodiesterase. Fund Clin Pharmacol
2005; 19: (in press) Khalid A, Ghayur MN, Mesaik MA,
Kalauni SK, Atta-ur-Rahman, Gilani AH, Manandhar MD, Choudhary MI.
Sarcorucinine-D: a noncompetitive cholinesterases inhibitor that blocks
β-amyloid binding sites and calcium channels. Biochem Biophys Res Commun
2005 (in press). Iqbal Z, Lateef M, Jabbar A, Ghayur,
MN, Gilani AH. In vivo anthelmintic activity of Butea monosperma against
trichostrongylid nematodes in sheep. Fitoterapia 2005 (in press) Gilani,
AH, Khan A, Shah AJ, Jabeen Q. Blood pressure lowering effect of olives
is mediated through calcium channel blockade. Int J Food Sci Nutr 2005
(in press)
Begum S, Hassan SI,
Siddiqui BS, Ifzal R, Perwaiz S, Kiran T, Shaheen F, Ghayur MN,
Gilani AH. Preparation, Structure and Spasmolytic Activity of Some
Derivatives of Harmine Series of Alkaloids. J Nat Prod 2005; (in press). Ghayur
MN, Gilani AH. Radish seed extract mediates its cardiovascular
inhibitory effects via muscarinic receptor activation. Fund Clin
Pharmacol2005 (in press). Ghayur MN, Gilani AH, Khan A,
Amor EC, Villaseñor IM, Choudhary MI. Presence of calcium antagonist
activity explains the use of Syzygium samarangense in diarrhea.
Phytother Res 2005 (in press). Gilani, AH, Khan, A,
Ghayur, MN. Calcium antagonist and cholinomimetic activities in rabbits
explains the medicinal uses of olives in gut disorders. Nut Res 2005 (in
press) Ghayur MN, Gilani AH. Gastrointestinal
stimulatory and uterotonic activities of dietary radish leaves extract
are mediated through multiple pathways. Phytother Res 2005; 19: 750-755.
Iqbal
Z, Lateef M, Akhtar MS, Ghayur MN, Gilani AH. In vivo anthelmintic
activity of ginger against gastrointestinal nematodes of sheep. J
Ethnopharmacol 2005; (in press) Atta-ur-Rahman, Khalid A,
Sultana N, Ghayur MN, Mesaik MA, Khan MR, Gilani AH, Choudhary MI. New
natural cholinesterase inhibiting and calcium channels blocking
quinoline alkaloids. J Enz Inhib Med Chem 2005; (in press) Taqvi
SIH, Ghayur MN, Gilani AH, Aftab MT, Saify ZS. Synthesis, spasmolytic,
cardio-suppressant, vasodilator and Ca++ antagonist activities of
1-[4´-methylphenacyl]-4-acetyl -4-phenylpiperidinium bromide. Pak J Biol
Sci 2005; 8: (in press) Taqvi SIH, Aftab MT, Ghayur MN,
Gilani AH, Saify ZS. Synthesis and pharmacological screening of 1-(2´,
s4´-dimethoxyphenacyl)-4-hydroxy-4-phenylpiperidinium bromide. Int J
Pharmacol 2005; 2: (in press) Taqvi SIH, Aftab MT, Ghayur
MN, Gilani AH, Saify ZS. Synthesis and biological evaluation of 1-(2´,
4´-dimethoxyphenacyl)-4-acetyl-4-phenylpiperidinium bromide in
intestinal and cardiovascular tissues. J Pharmacol Toxicol 2005; (In
press)
Patents:
Antihypertensive composition containing thiocarbamate glycoside from Moringa oleifera.
Shaheen Faizi, B.S. Siddiqui, A.H. Gilani and R., Saleem, Pakistan Patent (1997), Patent Application No. 872/98 (25-8-98), S.I. No.136438.
Antihypertensive medicine Brassico, based on Brassica rapa sb. sp. campestris. A.H.
Gilani, Irfanullah, F. Shaheen, S. Bibi, and Shaheen Faizi Pakistan Patent (1998). Patent Application No. 871/98 (25-8-98), S.I. No. 136437.
More Papers (Related to specific areas of research)
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