​​The goals of the Centre for Bioinformatics and Computational Biology 

The aim of the group was to establish biorepository as a scientific field at AKU and particularly to: 

  • Identify the genetic markers of health and disease relevant to maternal and child populations
  • Employ a multi-omics approach encompassing genomics, transcriptomics, proteomics, and metabolomics using integrative machine learning strategies
  • Analyze omics data at the Aga Khan University and utilize it to resolve population level health concerns
The objectives of the centre are to:

  1. Consolidate the Medical College-wide bioinformatics resources under one roof so that all researchers can benefit through a pay-per-service model.
  2. Strengthen local capacity in Bioinformatics by conducting workshops and offering internships.
  3. Develop a graduate-level Bioinformatics course that can be taught across streams in MPhil/PhD programs at AKU.
  4. Develop user-friendly analysis platforms and Bioinformatics pipelines.
  5. Attract funding to support the sustainability and growth of the centre.
  6. Develop national and international collaborations and increase the global footprint of the centre.
  7. Organize seminars and conferences to disseminate the information generated at the centre and invite global experts to share their knowledge.
Our approach is to generate a multi-disciplinary research capacity at the centre in omics data analysis and its interpretation. We aim to prepare a consolidated list of all research groups at the Medical College that could benefit from in-house Bioinformatics analysis and curate a list of software, reference datasets, and Bioinformatics pipeline that can be beneficial for the end-user. 

We aim to establish quality control metrics and standards to benchmark Bioinformatics pipelines and tools. We are working in collaboration with the departments of Pathology and Laboratory Medicine to expand next-generation sequencing or NGS-based diagnostics for humans and pathogen genomics for clinical diagnostics. 

We are also engaged with local, provincial, and national policymakers to promote Bioinformatics skills and next-generation sequencing (NGS) data analyses to address focused research questions.

Our aim is to become a regional centre of excellence in Bioinformatics and build capacity in the field.

​We hope to maintain a Pakistan build for SARS-CoV-2 sequences at Nextstrain.org.​