Sheerien Rajput, PhD, is a cell and molecular biologist and an Assistant Professor at the Centre
for Regenerative Medicine and Stem Cell Research, AKU. Her work focuses on the biology of
stem cells, cancer stem cells and microenvironments to understand tissue regeneration, disease
heterogeneity and therapeutic resistance in cancers.
Dr Rajput completed her PhD at the Faculty of Health Sciences, Aga Khan University, where she
investigated the crosstalk between Mucin 1 (MUC1) and X-box binding protein 1 (XBP1) in
cancers. During her doctoral work, she established Pakistan’s first myeloma cell line, AKUMY01, derived from bone marrow. She also conducted a large retrospective
immunohistochemical study to evaluate the expression and prognostic significance of
biomarkers in multiple myeloma (MM) patients and used third-generation lentiviral RNA
interference (RNAi) approaches to study the functional role of candidate markers.
She joined CRM as a Postdoctoral fellow in 2020, where she lead the team in establishing Tissue
engineering core lab facility equipped with 3D Bioprinter. She was appointed as an Assistant
Professor at AKU CRM in 2021.