This research will help in understanding:
The full genetic architecture of cells in normal placentas
The favoured aneuploidy chromosomes during the invasion
How are chromosomes organised in the placental cells?
If the chromosomes alter position due to aneuploidy and if there is any contact between specific chromosomes
Diseases relating to abnormal placentation during fetal development
The team is using high-end imaging technology in combination with cytogenetics for mapping the chromosomes. It has managed to set up different cytogenetic strategies for mapping single cells by karyotyping using multicolour FISH.