Dr Hammad Hassan
Dr Hammad Hassan completed his Masters in Biochemistry from the Institute of Chemical Sciences, University of Peshawar in 2003. He proceeded to complete his MS in Biotechnology from the National Institute for Biotechnology and Genetic Engineering, Faisalabad in 2005.
In 2006, he was awarded Overseas PhD Scholarship to Austria by the Higher Education Commission, where he completed his PhD at the laboratory of Professor Dr Wilfried Ellmeier at the Institute of Immunology, Medical University of Vienna, Austria in 2011. He then continued his Postdoctoral fellowship in the same laboratory till 2013. He returned to Pakistan and joined the Department of Biochemistry, Abdul Wali Khan University, Mardan as Assistant Professor. Dr
Hassan has more than 12 years of research experience in the field of molecular biology, immunology, and genetic engineering. He has published in highly reputed journals in his area of research focus and is a member of the Austrian Society of Immunology.
Dr Hassan’s research interest is to understand how different immune cells contribute to the process of tissue regeneration following infections, and how these immunological factors contribute to the cellular plasticity of resident tissue cells. This issue will be particularly important for stem cell studies and regenerative medicinal therapies.
Müller L, Hainberger D, Stolz V, Hamminger P, Hassan H, Preglej T, . . . Ellmeier W (2017). The corepressor NCOR1 regulates the survival of single-positive thymocytes. Scientific Reports,7(1). 15918-0. Link
Sakaguchi S, Hombauer M, Hassan H, Tanaka H, Yasmin N, Naoe Y, . . . Ellmeier W (2014). A novel Cd8-cis-regulatory element preferentially directs expression in CD44hiCD62L+ CD8+ T cells and in CD8αα+ dendritic cells. Journal of Leukocyte Biology, 97(4), 635-644. Link
Boucheron N, Tschismarov R, Göschl L, Moser MA, Lagger S, Sakaguchi S, Hassan H . . . Ellmeier W (2014). CD4+ T cell lineage integrity is controlled by the histone deacetylases HDAC1 and HDAC2. Nature Immunology, 15(5), 439-448. Link
Abramova A, Sakaguchi S, Schebesta A, Hassan H, Boucheron N, Valent P, . . . Ellmeier W (2013). The Transcription Factor MAZR Preferentially Acts as a Transcriptional Repressor in Mast Cells and Plays a Minor Role in the Regulation of Effector Functions in Response to FcεRI Stimulation. PLoS ONE, 8(10). Link
Hassan H, Sakaguchi S, Tenno M, Kopf A, Boucheron N, Carpenter AC, . . . Ellmeier W (2011). Cd8 enhancer E8I and Runx factors regulate CD8a expression in activated CD8+ T cells. Proceedings of the National Academy of Sciences, 108(45), 18330-18335. Link
Sarah Yousuf completed her BS in Biotechnology from University of Karachi in 2015 and MSc. in Molecular Bioengineering from Technische Universität Dresden in the year 2018. During her Masters, she worked on zebrafish model in order to study the functional recovery after retina regeneration. In 2020, Sarah joined the Centre for Regenerative Medicine as a Research Associate and work as a part of Dr Hammad Hassan's team. Here at AKU-CRM, she intends to use the stem cells and differentiate them in vitro into functional Red Blood cells. Generation of RBCs in vitro would serve as an alternative approach to blood transfusion and hence to better and safer treatment of patients.