Aga Khan University School of Nursing (AKU-SON) was the first academic unit of the University in operation beginning in 1980. At present, AKU-SON conducts four academic programmes, General Nursing (RN) Diploma, BSc in Nursing (Post RN), BSc in Nursing and MSc in Nursing. In addition, a preparatory programme, Track 1 (eighteen weeks), is offered for students from underprivileged areas to enable them to cope with the academic demands of the RN Diploma programme.

Since the establishment of School of Nursing, 2,232 students have graduated from AKU-SON.