Medical College
 
 

Biological and Biomedical Sciences

 

Faculty

Dr. Sohail A. Qureshi
Associate Professor

Department of Biological and Biomedical Sciences
Aga Khan University
Stadium Road, P.O. BOX 3500
Karachi 74800, Pakistan

Phone: 92-21-4864464 or 4930051 Ext. 4464
Appointments: 4864461 (Direct line) or 4930051 Ext. 4461
Fax: 92-21-4934294
Email: sohail.qureshi@aku.edu


Academic Qualification and Training

Ph.D. 1990 University of Maine, USA
Master of Science 1984 Quaid-I-Azam University, Islamabad, Pakistan
B.Sc. 1982 Champlain College, Quebec, Canada

Training

Senior Scientist (2001-2003)
Invitrogen Corporation, Madison, Wisconsin (USA)

Assistant Research Professor (1997-2001)
Dept. of Neurology, Univ. of Wisconsin Medical School, Madison, USA

Senior Research Fellow (1993-1997)
Wellcome/CRC Institute, University of Cambridge, UK

Senior Postdoctoral Fellow (1992-1993)
Imperial Cancer Research Fund, London, UK

Postdoctoral Research Associate (1989-1992)
Institute of Genetics, University of Glasgow, Scotland, UK

Discipline

Biochemistry, Molecular and cellular biology

Research Interests

Regulation of gene expression in eukaryotes and archaea
Molecular basis of epileptogenesis
Vaccine development against hepatitis C and E

Honours And Awards

Imperial Cancer Research Fund Postdoctoral Fellow (April 1993)
Fred Griffee Award (May 1987)

Publications

  • QURESHI, S.A., Sanders, P., Zeh, K., Whitney, M., Pollock, B., Desai, R., Whitney, P., Robers, M., Hayes, S.H. (2003). A one-arm homologous recombination approach for developing nuclear receptor assays in somatic cells. Assay & Drug Development Technologies 1(6):767-776
  • Roberti, M., Polosa, P. L., Musicco, C., Milella, F., QURESHI, S. A., Gadaleta, M. N., Jacobs, H. T., and Cantatore, P.  (1999). In vivo mitochondrial DNA-protein interactions in sea urchin eggs and embryos. Current Genetics 34: 449-458.
  • QURESHI, S. A., and Jackson, S. P.  (1998). Sequence-specific DNA binding by the Sulfolobus shibatae TFIIB homologue, TFB, and its effect on promoter strength. Molecular Cell 1:389-400.
  • QURESHI, S.A., Bell, S.D., and Jackson, S.P.  (1997). Factor requirements for transcription in the archaeon Sulfolobus shibataeEMBO Journal 16:2927-2936.
  • QURESHI, S. A., Khoo,B., Baumann, P., and Jackson S. P. (1995). Molecular cloning of the TFIIB homologue from Sulfolobus shibatae. Proceedings of the National Academy of Sciences (USA) 92:6077-608      
  • QURESHI, S. A., Baumann, P., Rowlands, T., Khoo, B., and Jackson, S. P. (1995). Cloning and functional analysis of the TATA-binding protein from Sulfolobus shibataeNucleic Acids Research 23:1775-1781.  
  • Baumann, P., QURESHI, S. A., and Jackson, S. P.  (1995). Transcription - New insights from archaebacteria.  Trends in Genetics 11(7):279-283.
  • QURESHI, S. A., and Blake, R. D. (1995).  Sequence characteristics of a cervid DNA repeat family and its relationship to a similar family in Bovids.  Journal of Molecular Evolution 40:400-404.
  • QURESHI, S. A., and Jacobs, H. T.  (1993). Two distinct, sequence-specific DNA-binding proteins interact independently with the major replication pause region of sea urchin mtDNA.  Nucleic Acids Research 21:2801-2808.
  • QURESHI, S. A., and Jacobs, H. T.  (1993). Characterization of a high-affinity binding site for a DNA-binding protein from sea urchin embryo mitochondria.  Nucleic Acids Research 21: 811-816.

Book Chapters

  • El Meziane, A., QURESHI, S. A., Segreto, D. T., and Jacobs, H. T.  (1991). Protein-nucleic acid interactions in sea urchin mitochondria. In: Recent Advances in Cellular & Molecular Biology, eds. Wegmann, R. J. and Wegmann, M. A. (Peeters Press, Paris) Vol. 2, pp. 103-110.

Patents

  • SOHAIL A. QURESHI and Thomas P. Sutula. Diagnostic and prognostic methods and compositions for seizure- and plasticity-related disorders. Patent number P01178WO (November 2004).
  • SOHAIL A. QURESHI and Steve Hayes. High-throughput Glucocorticoid receptor and mineralocorticoid receptor cell-based assays utilizing -lactamase reporter. Patent number to be assigned (submitted July 2003).

AKU - Medical College 'Biological and Biomedical Sciences'

 

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